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| REVIEW ARTICLE |
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| Year : 2015 |
Volume
: 8 | Issue : 1 | Page
: 18-24 |
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Application of gel-based proteomic technique in female reproductive investigations
Arianmanesh Mitra1, Mandana Beigi Boroujeni2
1 Department of Anatomical Sciences, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
2 Department of Anatomical Sciences, School of Medicine, Lorestan University of Medical Sciences, Khoram Abad, Iran
Correspondence Address:
Arianmanesh Mitra
Department of Anatomical Sciences, School of Medicine, Zanjan University of Medical Sciences, Zanjan
Iran
 Source of Support: Study by Arianmanesh carried out in Paul A. Fowler
laboratory was supported by NHS Grampian R and D (project number
RG05/019)., Conflict of Interest: None  | Check |
DOI: 10.4103/0974-1208.153121
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Recently, gel-based proteomics has been increasingly applied to investigate proteins involved in female reproductive tract in healthy and disease states. Gel-based proteomics coupled by mass spectrometry (MS) facilitate the identification of new proteins playing roles in cellular and molecular interactions underlying female reproductive biology and it is a useful method to identify novel biomarkers of diseases by studying thousands of proteins simultaneously involved in female reproductive tract in healthy state compared to disease state. This review will discuss the best studies areas contributed to female reproductive biology in which gel-based proteomics coupled by MS has been applied to generate proteome of female reproductive tract in a healthy state. |
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