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| CASE REPORT |
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| Year : 2016 |
Volume
: 9 | Issue : 2 | Page
: 128-130 |
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A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
Dalvi Rupa, Koppaka Neeraja, Chavan Deepak, Mandava Swarna
Department of Cytogenetics, Cytogenetic Division, SRL Limited, Mumbai, Maharashtra, India
Correspondence Address:
Mandava Swarna
Department of Cytogenetics, SRL Limited, Prime Square Building, Plot No. 1, Gaiwadi Industrial Estate, S. V. Road, Goregaon West, Mumbai - 400 062, Maharashtra
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-1208.183505
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BACKGROUND: Balanced non-robertsonian translocation (RT), involving acrocentric chromosomes, is a rare event and only a few cases are reported. Most of the RTs are balanced involving acrocentric chromosomes with the breakpoints (q10;q10). MATERIALS AND METHODS: Chromosome analysis was performed as per standard procedure – Giemsa-trypsin banding with 500 band resolution was analyzed for chromosome identification. RESULTS: In the present study, we report a rare balanced non-RTs involving chromosomes 13 and 15 with cytogenetic finding of 46, XX, t(13;15)(p11.2;q22.1). CONCLUSION: To the best of our knowledge, this is the first such report of an unusual non-RT of t(13:15) with (p11.2;q22.1) break points. |
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