Journal of Human Reproductive Science
Home Ahead of Print Current Issue Archives
   Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size    Users online: 938

ORIGINAL ARTICLE Table of Contents   
Year : 2021  |  Volume : 14  |  Issue : 4  |  Page : 372-379
Age-specific distribution of serum anti-mullerian hormone and antral follicle count in Indian infertile women

1 Department of Reproductive Medicine, Gunasheela Surgical and Maternity Hospital, Bengaluru, Karnataka, India
2 Department of Biochemistry, Gunasheela Surgical and Maternity Hospital, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Rajaam Murali
Gunasheela Surgical and Maternity Hospital, No. 1 Dewan N Madhava Rao Road, Basavanagudi, Bengaluru - 560 004, Karnataka
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jhrs.jhrs_65_21

Rights and Permissions

Background: Ovarian reserve declines with age. However, there are considerable ethnic differences in the decline of ovarian reserve between individuals. Aim: This study aimed to make age-specific percentile charts of anti-Mullerian hormone (AMH) and antral follicle count (AFC) in Indian infertile women and to find the proportion of young women with low ovarian reserve. Setting and Design: This was a retrospective data analysis of AMH and AFC of 5525 infertile women from August 2015 to December 2018. Materials and Methods: Infertile women aged 20–44 years, with body mass index 18–32 kg/m2 and having both ovaries were included in the study. Women with pituitary/adrenal disorders, malignancy, total AFC >40, tuberculosis, endometriosis, autoimmune disorders, smoking, chemotherapy, radiotherapy and recent ovarian surgery were excluded from the study. Statistical Analysis: Comparison between groups was done by Chi-square test. Results: About 14.5% of women <35 years and 50.5% of women >35 years had low AMH values (<1.1 ng/ml). In addition, 5.6% of women <35 years and 23.6% of women >35 years had a low AFC of ≤5. In this study, 55.7% of women who had low AMH and 50.7% who had low AFC were <35 years of age. The median AMH values were 4.23 ng/mL in 20–25 years' age group, 3.48 ng/mL in women aged 26–30 years, 2.43 ng/mL in women aged 31–35 years, 1.28 ng/mL in women aged 36–40 years and0.52 ng/mL in 40–44 years' age group. The median AFCs were 20, 18, 14, 10 and 6 for each of the age groups, respectively. Conclusion: This study suggests that approximately more than half of the infertile women who were tested to have low ovarian reserve were <35 years of age.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded156    
    Comments [Add]    

Recommend this journal