Journal of Human Reproductive Science
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CASE REPORT Table of Contents   
Year : 2021  |  Volume : 14  |  Issue : 4  |  Page : 443-445
Drug-free in vitro activation for primary ovarian insufficiency

Department of Reproductive Medicine and Akanksha Hospital and Research Institute, Anand, Gujarat, India

Correspondence Address:
Dr. Niket H Patel
Akanksha Hospital and Research Institute, Near Shristi English Medium School Opp. Guruvilla Bungalows, Lambhvel, Anand - 387 310, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jhrs.jhrs_56_21

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Primary Ovarian Insufficiency (POI) or Diminished Ovarian Reserve (DOR) are the two conditions that affects women leading to infertility due to the lack of follicular growth and ovulation. Egg / Oocyte donation remains an option for these patients. However, with the development in Reproductive medicine various novel technologies like Ovarian Cryopreservation, Fragmentation, in vitro activation with drug treatment or even drug free autotransplantation enables the possibility of activating the pool of primordial follicles that can lead to successful pregnancy outcomes. Here, we report a case of women with POI, in which drug free in vitro activation of follicles was performed, followed by autotransplantation, which resulted in successful pregnancy. This is first case report from India that shows the procedure works and can be tried for women with POI.

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