Journal of Human Reproductive Science
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Year : 2021  |  Volume : 14  |  Issue : 5  |  Page : 31-47
Indian society for assisted reproduction consensus guidelines on preimplantation genetic testing in in vitro fertilization clinics


1 Managing Director, Rainbow IVF, Agra, Uttar Pradesh, President ISAR (2019), India
2 MBBS, MCE, Chief Embryologist & Director-Rainbow IVF, Agra (Uttar Pradesh), India
3 MCE, PHD, Center of IVF and Human Reproduction, Sir Ganga Ram Hospital, New Delhi, India
4 Chief Medical Geneticist and PGT Head, Craft Hospital and Research Centre, Kerala, India
5 Freelance Consultant, Clinical Embryology, Chief Embryologist (Visiting): NIMS & EVAA Fettility Clinic & Research Center, NIMS University Jaipur, Chief independent auditor & Lab supervisor - (I) Motherhood Women’s Health & Child Care Center Science City Road Ahmedabad (II) Srijan Fertility & Research Center, Kankarbagh, Patna (III) Srishti IVF, Srishti Hospital, Paltan Bazaar Dibhrugarh, India
6 Embryology Laboratory Director & Clinical Research Head, Cellsure Biotech Research Centre, Mumbai, India
7 Bihar Head and Laboratory Director, Indira IVF group , Bihar State, Patna, Bihar, India
8 Scientific Director, Vaunshdhara’s Fertility Centre Pvt Ltd, Nagpur, India
9 Reproductive Geneticist, Director - Clinical Genomics & Molecular Diagnostics, Lifenity Wellness International, Mumbai, India
10 Senior Consultant & Chief Embryologist, Artemis Health Institute, Gurugram, Haryana, India
11 MCE (Leeds University, UK); Senior Clinical Embryologist at ARMC Aegis Hospital, Perinthalmanna ARMC IVF, Calicut, Kerala, India
12 MSc, PhD., Laboratory Director, Fertility Clinic, Mumbai, India
13 MBBS, MS (OBG), Sr Consultant & Scientific Director, CIMAR Fertility Centre, Kochi, India
14 Scientific Head and Clinical Embryologist, Oasis Fertility, Pune, India
15 MD DNB MCE MNAMS FICOG, Associate Director, Scientific and Clinical Head, GG Hospital, Fertility Research and Women’s Speciality Center, Chennai, India

Correspondence Address:
Dr. Keshav Malhotra
MBBS, MCE, Chief Embryologist & Director-Rainbow IVF, Agra (Uttar Pradesh)
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-1208.330503

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Study Question: What are the good practice guidelines for Pre implantation genetic testing applicable in INDIA? What is Already Known: Pre-Implantation Genetic Testing (PGT) is not new in India. It is used to identify euploid embryos for transfer, thus enabling couples to achieve a healthy pregnancy. There has been a lot of controversy surrounding PGT in the international forums; most of these debates have failed to reach a consensus on whether PGT should be offered or its concerns be validated more. Study Design, Size, Duration: This is the report of a 2-day consensus meeting where two moderators were assigned to a group of experts to collate information on Pre implantation genetic testing and embryo biopsy practices in INDIA. This meeting utilised surveys, available scientific evidence and personal laboratory experience into various presentations by experts on pre-decided specific topics. Participants/Materials, Setting, Methods: Expert professionals from ISAR representing clinical, embryological and genetic fields. Main Results and the Role of Chance: The report is divided into various components defining the terminologies, the various requirements, qualifications, recommendations on PGT -A,M,SR, and quality management: the report and recommendations of the expert panel reflect the discussion on each of the topics and try to lay down good practice points for labs to follow. Limitations, Reasons for Caution: The recommendations are solely based on expert opinion. Future availability of data may warrant an update of the same. Wider Implications of the Findings: These guidelines can help labs across the country to standardise their PGT services and improve clinical outcomes. Study Funding/Competing Interest(S): The consensus meeting and writing of the paper was supported by funds from CooperSurgical India.


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