Journal of Human Reproductive Sciences

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 14  |  Issue : 3  |  Page : 244--249

Does the serum vitamin D status and its possible effect on serum anti-müllerian hormone levels predict fertility in premenopausal women?


Oyinkansola Islamiyat Lawal 
 Department of Obstetrics and Gynaecology, University of Ibadan; Reproductive Biology Unit, Pan African University, Life and Earth Science Institute (Including Health and Agriculture), University of Ibadan, Ibadan, Oyo State, Nigeria

Correspondence Address:
Dr. Oyinkansola Islamiyat Lawal
Department of Obstetrics and Gynaecology University of Ibadan, Ibadan, Oyo State; Reproductive Biology Unit, Pan African University, Life and Earth Science Institute (Including Health and Agriculture), University of Ibadan, Ibadan, Oyo State
Nigeria

Context: Evidence suggests that serum Vitamin D level influences female reproduction. However, clinical studies have reported conflicting evidence on the effect of serum Vitamin D levels on serum Anti-Müllerian hormone (AMH), with little evidence in African women. Aim: The study aimed to compare the relationship between serum Vitamin D and serum AMH among infertile and fertile women. Settings and Design: This comparative cross-sectional study analyzed data from 170 premenopausal women; 81 infertile, and 89 fertile women attending a Nigerian tertiary hospital between March and June 2019. Materials and Methods: Serum AMH and 25-hydroxyvitamin D (25(OH) Vitamin D) concentrations were analysed using enzyme-linked immunosorbent assay. Statistical Analysis: Statistical analysis was done using SPSS version 25 for windows. Categorical variables were summarized in frequencies and proportions while continuous variables were summarized in means ± standard deviation and median (interquartile range). The association was explored using linear regression. The level of significance was set at 0.05. Results: The prevalence of Vitamin D deficiency (<20 ng/ml) in infertile women and fertile women was 16% and 18%, respectively. There was no difference in serum Vitamin D levels between infertile and fertile women in this study after controlling for age and body mass index (BMI) (P = 0.186). There was no association between serum 25(OH) Vitamin D and serum AMH in infertile (B = 0.002; P = 0.474) and fertile women (B = ‒0.002; P = 0.522) after adjusting for age and BMI. Conclusion: Infertile and fertile women had similar serum Vitamin D levels and there was no relationship between serum Vitamin D and serum AMH in both infertile and fertile women.


How to cite this article:
Lawal OI. Does the serum vitamin D status and its possible effect on serum anti-müllerian hormone levels predict fertility in premenopausal women?.J Hum Reprod Sci 2021;14:244-249


How to cite this URL:
Lawal OI. Does the serum vitamin D status and its possible effect on serum anti-müllerian hormone levels predict fertility in premenopausal women?. J Hum Reprod Sci [serial online] 2021 [cited 2022 Aug 15 ];14:244-249
Available from: https://www.jhrsonline.org/article.asp?issn=0974-1208;year=2021;volume=14;issue=3;spage=244;epage=249;aulast=Lawal;type=0